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P. vivax (malaria) infected human blood smears

Accession number BBBC041 · Version 1 Example images Description of the biological application Malaria is a disease caused by Plasmodium parasites that remains a major threat in global health, affecting 200 million people and causing 400,000 deaths a year. The main species of malaria that affect...

Human U2OS cells – compound-profiling Cell Painting experiment

Accession number BBBC022 · Version 1 Example Images Hoechst 33342 staining con A staining SYTO 14 staining WGA + phalloidin staining MitoTracker Deep Red staining Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular...

FiloData3D - Single A549 cells with filopodia (synthetic image data)

Accession number BBBC046 · Version 1 Example images The synthetic time-lapse image data of a CRMP-2-phospho-defective cell for the given fluorescence level facto(F) and anisotropy ratio (AR). The synthetic image data of a CRMP-2-phospho-defective cell for varying anisotropy ratios (ARs). The...

Human MCF7 cells – compound-profiling experiment

Accession number BBBC021 · Version 1 Example Images Actin disrupter Aurora kinase inhbitor Eg5 inhibitor Tubulin destabilizer Tubulin stabilizer Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each...

Human U2OS cells – Gene overexpression profiling experiment

Accession number BBBC037 · Version 1 Example images Description of the biological application The image set can be used to functionally annotate the genes through comparing their overexpression morphological profiles. Images Images from five fluorescent channels were captured at 20x magnification on...

Mouse Embryos

Accession number BBBC003 · Version 1 Example images . DIC Image Foreground Biological application Fluorescence microscopy cannot be used to image human embryos to determine embryo viability for in vitro fertilization because the introduction of exogenous fluorescent dyes is considered a toxic...

C. elegans live/dead assay

Accession number BBBC010 · Version 1 Example images Positive: mostly alive Negative: mostly dead Biological application This selection of images are controls selected from a screen to find novel anti-infectives using the roundworm C.elegans . The animals were exposed to the pathogen Enterococcus...

Human HT29 colon-cancer cells (diverse phenotypes)

Accession number BBBC018 · Version 1 Example Images ​ ​ ​ ​ ​ Actin blebs Actin dots Anaphase/Telephase Angular Cell Edges Cresent Nuclei ​ ​ ​ ​ ​ Long Projections Metaphase Motile Peas in a Pod Peripheral Actin ​ ​ ​ ​ Large Spread Phospho-histone H3 dots Prometaphase Prophase Biological...

Chinese Hamster Ovary Cells

Accession number BBBC030 · Version 1 Example images DIC image Ground truth Images The image set consists of 60 Differential Interference Contrast (DIC) images of Chinese Hamster Ovary (CHO) cells. The images are taken on an Olympus Cell-R microscope with a 20x lens at the time when the cell...

C. elegans metabolism assay

Accession number BBBC011 · Version 1 Example images Negative control: wild type Positive control: fat Biological application Images are controls from an RNA interference screen for genes affecting fat mass in the nematode C.elegans. The animals are stained with oil red O, a non-flourescentdye which...